Therapeutic benefits of proning to improve pulmonary gas exchange in severe respiratory failure: focus on fundamentals of physiology

RMG Berg, JP Hartmann, UW Iepsen… - Experimental …, 2022 - Wiley Online Library
… redistribution of perfusion. In anaesthetised and mechanically ventilated healthy individuals,
a vertical urn:x-wiley:09580670:media:eph13057:eph13057-math-0003 ratio gradient is …

[HTML][HTML] Quantitative CT-based image registration metrics provide different ventilation and lung motion patterns in prone and supine positions in healthy subjects

KM Shin, J Choi, KJ Chae, GY Jin, A Eskandari… - Respiratory …, 2020 - Springer
… resting gradient in ventral-dorsal lung expansion when shifting a human from the supine to
the prone body posture [9, 10]. In contrast to effects on lung aeration, pulmonary blood flow is …

[HTML][HTML] Comparison of phase-resolved functional lung (PREFUL) MRI derived perfusion and ventilation parameters at 1.5 T and 3T in healthy volunteers

J Glandorf, F Klimeš, A Voskrebenzev, M Gutberlet… - PloS one, 2020 - journals.plos.org
… 2d FLASH lung MRI were acquired from 15 healthy subjects at … ), perfusion (Q), quantified
perfusion (Q Quant ), perfusion … (VDP) and ventilation-perfusion match (VQM) were compared …

Oxygen‐enhanced functional lung imaging using a contemporary 0.55 T MRI system

I Bhattacharya, R Ramasawmy, A Javed… - NMR in …, 2021 - Wiley Online Library
… seven healthy volunteers We evaluated the relationship between lung volume (ie lung tissue
density) and lungpulmonary blood volume and perfusion via vasodilation. This increase in …

Abnormal pulmonary perfusion heterogeneity in patients with Fontan circulation and pulmonary arterial hypertension

SR Hopkins, RC Sá, GK Prisk, AR Elliott… - The Journal of …, 2021 - Wiley Online Library
human subjects without contrast injection or ionizing radiation. For this reason, it is suitable
for evaluating the distribution of pulmonary perfusion … others with pulmonary vascular disease…

Echo Time‐Dependent Observed Lung T1 in Patients With Chronic Obstructive Pulmonary Disease in Correlation With Quantitative Imaging and Clinical Indices

SMF Triphan, O Weinheimer… - Journal of Magnetic …, 2021 - Wiley Online Library
… A reference value taken from young healthy volunteers would result in almost all lung area
… -contrast enhanced tool for the analysis of lung perfusion, while also providing the possibility …

Dynamic contrast enhanced MRI for the evaluation of lung perfusion in idiopathic pulmonary fibrosis

LA Torres, KE Lee, GP Barton, AD Hahn… - … Respiratory Journal, 2022 - Eur Respiratory Soc
… Quantitative PBF and semiquantitative FMTT perfusion also clearly delineated healthy
subjects from IPF patients. Moreover, decreased FMTT was found in the subset of IPF patients …

Proton MRI of the lung: how to tame scarce protons and fast signal decay

A Voskrebenzev… - Journal of Magnetic …, 2021 - Wiley Online Library
… (21% O 2 ) is found for the healthy volunteer (c), some regions of … a gravitational vertical
gradient in healthy volunteers and … regional pulmonary blood flow due to pulsatile blood flow and …

Perfusion quantification using voxel‐wise proton density and median signal decay in PREFUL MRI

J Glandorf, F Klimeš, L Behrendt… - Magnetic …, 2021 - Wiley Online Library
… We proposed a new approach for perfusion quantification of phase-resolved functional lung
… It depends on flow velocity varying from 1 m/s in healthy subjects up to > 4 m/s in patients …

Dynamic lung water MRI during exercise stress

F Seemann, A Javed, JM Khan… - Magnetic …, 2023 - Wiley Online Library
… to healthy subjects and patients with compensated heart failure to quantify lung water … ,
further reflects a global increase in pulmonary perfusion during exercise. The decrease in left …